Moderna’s vaccine is effective against new variants of the coronavirus that have emerged in Britain and South Africa, the company announced on Monday. But it appears to be less protective against the variant discovered in South Africa, and so the company is developing a new form of the vaccine that could be used as a booster shot.
“We’re doing it today to be ahead of the curve should we need to,” Dr. Tal Zaks, Moderna’s chief medical officer, said in an interview. “I think of it as an insurance policy.”
He added, “I don’t know if we need it, and I hope we don’t.”
Moderna reported findings from a study that used blood samples from eight people who had received two doses of the vaccine, and two monkeys that had also been immunized.
The variant found in Britain had no effect on the levels of neutralizing antibodies — the type that can disable the virus — produced after vaccination. But with the form from South Africa, there was a sixfold reduction in those levels.
Even so, the company said, those antibodies “remain above levels that are expected to be protective.”
Moderna collaborated on the study with the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.
The results have not yet been published or peer-reviewed, but have been submitted to bioRxiv, which posts preliminary studies online.
The company’s action is part of a race to control a shape-shifting virus that has already created global havoc and now threatens to mutate in ways that will make it even harder to fight.
In other vaccine news:
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The pandemic has inflicted the greatest labor crisis since the Great Depression, Guy Ryder, the head of the United Nations International Labour Organization, said on Monday. Mr. Ryder said the coronavirus has caused a loss of working hours equivalent to some 255 million jobs last year. There is still massive uncertainty about when the global economy will return to pre-pandemic levels of employment, but it won’t be in 2021, the agency said. Its analysis also pointed to the unevenness of the pandemic’s impact, with growth in the finance and I.T. sectors, underscoring the need for a targeted response to the crisis.
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Australia on Monday approved the Pfizer-BioNTech vaccine for use among people 16 and older, the country’s first coronavirus vaccine approval. Vaccinations are expected to start late next month. The announcement came one year to the day after Australia reported its first coronavirus case.
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After delays, Turkey received 6.5 million more doses of a Chinese-produced coronavirus vaccine Monday morning, the state-run news agency, Anadolu, reported. Turkey was expecting to receive at least 10 million doses of the vaccine in December, and 20 million more in January. But the batches were delayed and the number of doses remained below expectations, an apparent blow to China’s vaccine diplomacy. Turkey has given more than 1. 2 million inoculations, according to Health Ministry data, using the CoronaVac shot from the Chinese company Sinovac. Almost 2.5 million people in Turkey are infected with the coronavirus and more than 25,000 people have died, government data shows.
Livia Albeck-Ripka contributed reporting.
Merck announced on Monday that it was abandoning a pair of Covid-19 vaccines in clinical trials.
The news came as a disappointment at a time when the United States and other countries are struggling to accelerate their sluggish vaccination campaigns and new coronavirus variants threaten to bring surges over the next few months.
The two projects are the second and third vaccines to be abandoned in clinical trials. The University of Queensland in Australia abandoned its own effort in December. Sanofi and other vaccine makers have paused some projects after getting disappointing initial results but are now regrouping to move forward.
Merck was slower than other companies to get into the Covid-19 vaccine race. In June, it acquired the Austrian firm Themis Bioscience to develop a vaccine originally designed at Institut Pasteur, based on a weakened measles virus. Researchers began a Phase 1 trial in August. In a second effort, Merck partnered with IAVI, a nonprofit scientific organization that develops vaccines and treatments, on another vaccine. For that one, they used the same design that they successfully employed to make a vaccine for Ebola.
Merck and IAVI were awarded $38 million for their vaccine research, but neither of Merck’s projects earned the lavish support that Operation Warp Speed showered on other efforts from companies such as Moderna and Johnson & Johnson. In its announcement, Merck said that both vaccines looked safe in early clinical trials. But neither produced a strong response from the immune system. They decided that it was not worth going forward with large-scale trials that would demonstrate whether the vaccines protected people from Covid-19.
“We are grateful to our collaborators who worked with us on these vaccine candidates and to the volunteers in the trials,” Dr. Dean Y. Li, the president of Merck Research Laboratories, said in a statement.
Merck will instead focus its Covid-19 efforts on an experimental antiviral drug known as molnupiravir. Originally designed for influenza, it has shown promising effects in studies on animals and in early clinical trials. The trial is set to finish by May, although preliminary results could come out as early as March.
IAVI said it would continue searching for Covid-19 vaccines. “Our scientists will continue to evaluate other candidates to see if other routes of administration or changes to the construct could lead to improved immune response,” said Karie Youngdahl, senior director and head of global communications at IAVI.
California officials announced on Monday morning that they were lifting severe coronavirus restrictions on huge swaths of the state, home to tens of millions of people. The decision would allow restaurants in those areas to reopen for outdoor dining, and would give hair salons and other personal care businesses the green light to resume limited operations.
However, local officials can still opt to keep restrictions in place, based on conditions in individual communities.
“Seven weeks ago, our hospitals and frontline medical workers were stretched to their limits,” Dr. Mark Ghaly, the state’s secretary of health and human services, said in a statement. “But Californians heard the urgent message to stay home when possible, and our surge after the December holidays did not overwhelm the health care system to the degree we had feared.”
Effective immediately, state officials said, they were ending regional stay-at-home orders, which banned gatherings of any size and required residents to stay home except for essential work. The orders came into force when hospital intensive-care units in the region were projected to become dangerously full.
Such orders had been in effect for Southern California, a huge region encompassing Los Angeles, Orange County and San Diego, as well as for the San Joaquin Valley and the Bay Area. Counties in those regions will now return to a tiered system of rules tied to the prevalence of the virus in each county.
The move is a victory for restaurateurs, who have been pushing the governor to ease what they have said are arbitrary and unnecessary rules.
But it is also a sign that Gov. Gavin Newsom’s administration is struggling to keep a firm grip on a pandemic response that has been criticized as chaotic and piecemeal, undercutting what should be strong, clear public guidance.
The news came on the heels of a weekend of mixed signals from the state about its strategy to curb the rampant spread of the virus.
While California’s overall case numbers have been on the decline, hospitals in Southern California are still overwhelmed, and experts worry that new variants of the virus — including one that researchers recently found in more than half of test samples collected in Los Angeles — could threaten progress.
In the Bay Area, the amount of available intensive care unit capacity has risen to 23.4 percent, according to the state as of Sunday — well above the 15 percent threshold that triggered the stay-at-home order for the region. Yet the Sacramento area has just 11.9 percent intensive care unit capacity, and was allowed to exit the strict order more than a week ago.
Although The San Francisco Chronicle reported on Saturday that officials in the region were feeling hopeful that the order would be lifted soon, the state’s department of public health said on Sunday that the Bay Area wasn’t eligible to have restrictions loosened based on its projections.
Mr. Newsom has repeatedly said that the state’s reopening process would be guided by transparent data, but The Associated Press reported that Mr. Newsom’s administration has refused to disclose key data that officials are using to make decisions about restrictions.
And even after President Biden unveiled what experts have long said is a desperately needed national strategy for finally controlling the pandemic, there are still major hurdles in the vaccine rollout, which in California has contributed to continuing chaos, in which vaccine eligibility rules have been implemented differently county by county.
The state quietly rolled out a promised clearinghouse website to help people find vaccination appointments. But it’s still described as a pilot site.
The governor has been facing mounting political pressure from a recall effort. Experts have said that the vaccine rollout, as well as efforts to reopen, are key tests for his administration.
The European Commission, the executive arm of the European Union, recommended on Monday restricting nonessential travel in a bid to curb the spread of new more contagious variants of the coronavirus.
At the same time, the commission’s proposal aims to prevent blanket border closures, which would obstruct trade and the movement of cross-border workers. Traveling without restrictions would still be possible for family, work and health reasons, which are deemed essential.
“The situation in Europe with the new variants have led us to take difficult but necessary decisions,” Ursula von der Leyen, the president of the commission, wrote on Twitter. “We need to keep safe and discourage nonessential travel.”
The move came amid signs in Britain that Prime Minister Boris Johnson would announce an extension and tightening of lockdown rules in England. In the United States, President Biden has moved to restrict travel from Europe and South Africa over concerns about new variants. Also on Monday, Moderna announced that while its vaccine is effective against new variants, it appears to be less protective against the one that emerged in South Africa, raising further concern.
In the E.U. plan, countries and regions where the 14-day infection rate is more than 500 per 100,000 inhabitants would qualify as “dark red,” or high-risk zones, and moving between them should be limited to essential reasons, the commission said. At the same time, those coming in from outside the bloc, even for essential reasons, would have to undergo testing and quarantines. “The first recommendation is: don’t travel,” said Ylva Johansson, the bloc’s commissioner for home affairs.
The commission’s proposal is nonbinding and needs to be endorsed by national governments, who will discuss it Monday afternoon. It comes after last week’s meeting of the leaders of 27 European Union nations, who agreed in principle to selectively restrict nonessential travel, but did not decide on the details.
“There is currently a very high number of new infections across many member states,” said Didier Reynders, the bloc’s commissioner for justice. “There is an urgent need to reduce the risk of travel-related infections, to lessen the burden on overstretched health care systems.”
Freedom of movement is the cornerstone of the bloc, but travel restrictions remain the province of national governments and vary from country to country, creating a chaotic patchwork of measures. Belgium, for example, has announced a ban on nonessential travel coming into force this Wednesday, with fines for those who don’t comply.
China’s coronavirus vaccines were supposed to deliver a geopolitical win that showcased the country’s scientific prowess and generosity. Instead, in some places, they have set off a backlash.
Officials in Brazil and Turkey have complained that Chinese companies have been slow to ship the doses and ingredients. Disclosures about the Chinese vaccines have been spotty. The few announcements that have trickled out suggest that China’s vaccines, while considered effective, cannot stop the virus as well as those developed by Pfizer and Moderna, the American drugmakers.
In the Philippines, some lawmakers have criticized the government’s decision to purchase a vaccine made by a Chinese company called Sinovac. Officials in Malaysia and Singapore, which ordered doses from Sinovac, have had to reassure their citizens that they would approve a vaccine only if it has been proven safe and effective.
At least 19 countries, most of them low and middle income, signed deals with the Chinese vaccine companies because they offered access at a time when richer nations had claimed most of the doses made by Pfizer and Moderna. But the delays in getting the Chinese vaccines and the fact that the vaccines are less effective mean that those countries may take longer to vanquish the virus.
Beijing officials who had hoped the vaccines would burnish China’s global reputation are now on the defensive. The state news media has started a misinformation campaign against the American vaccines and promoting the Chinese vaccines as a better alternative. They have also distributed online videos that have been shared by the anti-vaccine movement in the United States.
The vaccines are also meant to prove that China has become a scientific and diplomatic powerhouse. It remains on par with the United States in the number of vaccines approved for emergency use or in late-stage trials. Sinopharm, a state-owned vaccine maker, and Sinovac have said they can produce up to a combined two billion doses this year, making them essential to the global fight against the coronavirus.
Unlike the Pfizer and Moderna vaccines, their doses can be kept at refrigerated temperatures and are more easily transported, making them appealing to the developing world.
China’s campaign has been plagued with doubts, however. A YouGov survey this month of roughly 19,000 people in 17 countries and regions showed that most were distrustful of a Covid-19 vaccine made in China. The misinformation campaign surrounding Western vaccines could further undermine its image.
Mexico’s president, Andrés Manuel López Obrador, said Sunday that he had contracted the coronavirus and was undergoing “medical treatment” for what he described as mild symptoms.
Mr. López Obrador, writing on Twitter, said he would continue to carry out his official duties, including holding a call with President Vladimir V. Putin of Russia that is set for Monday.
“As always, I am optimistic,” he said.
The Mexican leader has consistently played down the pandemic, questioning the value of wearing masks and refusing to wear one himself in most public appearances.
On Friday, he posted a photo of himself indoors, again without a mask, conducting a call with President Biden. He was accompanied by Marcelo Ebrard, the foreign minister, and Alfonso Romo, a former top aide — and neither was wearing a mask. And on Saturday, the president met with local business leaders in Monterrey.
Hours before disclosing that he had contracted the virus, Mr. López Obrador, who flies commercial on all official trips, sat in coach on a flight from San Luis Potosí to Mexico City, according to local media reports.
As late as June, Mr. López Obrador was still sounding dismissive. He said that having a clean conscience would help fight off the virus. “No lying, no stealing, no betraying, that helps a lot to not get coronavirus,” he told reporters.
And for months, the president has repeatedly insisted that the end of the pandemic’s devastation was just around the corner.
“The worst is ending,” he said this month, as deaths surged. “We are coming out of it.”
In the spring, The New York Times reported that the Mexican government had failed to record hundreds, possibly thousands, of deaths in Mexico City, dismissing officials who had tallied more than three times as many fatalities in the capital than the government had publicly acknowledged.
Then in December, federal officials, loath to damage the economy still further, reassured the public that Mexico City had not reached the level of contagion that would require a full lockdown. In fact, the government’s own numbers showed that the capital had surpassed that threshold, an analysis by The Times found.
Some public health experts said they were little surprised that Mr. López Obrador had become infected, given his preference for going mask free, even in situations where the risk of exposure was high.
“One even expected or assumed, because of his way of exposing himself to so many people and not wearing a mask, that he would have been infected earlier,” said Carlos Magis Rodríguez, professor of medicine at the National Autonomous University in Mexico. “In all the public appearances of López Obrador, except for when he went to visit Trump, we saw him without a face mask.”
He said there was reason for concern about the prognosis for Mr. López Obrador, who is 67 and had a heart attack in 2013. “He’s at greater risk than a young person,” Dr. Magis said.
Mr. López Obrador has told reporters that he will wait to get vaccinated with the rest of his age group, most likely in mid-March.
The news came as Mexico is confronting its worst moment since the pandemic began, with deaths hitting horrific highs. On Thursday, Mexico confirmed 1,803 new coronavirus deaths, surging past the previous record of more than 1,500 set days earlier.
And while the president is already being treated, many Mexicans are struggling to get medical care. The country’s hospitals are overrun, and close to 90 percent of beds in Mexico City, the epicenter of the national outbreak, are occupied.
Mexico has intentionally kept testing low throughout the pandemic, which has obscured the true extent of the virus’s reach across the country. But it is undeniable that Mr. López Obrador has presided over one of the worst outbreaks in the world.
To date, the country has recorded more than 1.7 million coronavirus infections and nearly 150,000 deaths, the fourth-highest global death toll.
Official numbers severely underestimate the true toll of the pandemic. As of December, the country had recorded 250,000 more deaths than expected, an excess mortality rate that suggests the pandemic has been far deadlier than official numbers suggest.
Kirk Semple and Elda Cantú contributed reporting.
An adviser to seven presidents and the nation’s top infectious disease expert for decades, Dr. Anthony S. Fauci has weathered many crises.
But in 2020, as one of the most familiar, trusted faces of the nation’s public health community, Dr. Fauci, 80, faced a year like no other when the coronavirus pandemic unfolded in the final months of the Trump administration amid an extremely divisive election season.
In an hourlong conversation with The New York Times over the weekend, Dr. Fauci described some of the difficulties, and the toll, of working with President Donald J. Trump.
In his first 48 hours in office, President Biden sought to project an optimistic message about returning the nation’s many homebound students to classrooms. “We can teach our children in safe schools,” he vowed in his inaugural address.
The following day, Mr. Biden signed an executive order promising to throw the strength of the federal government behind an effort to “reopen school doors as quickly as possible.”
But with about half of American students still learning virtually as the pandemic nears its first anniversary, the president’s push is far from certain to succeed. His plan is rolling out just as local battles over reopening have, if anything, become more pitched in recent weeks.
Teachers are uncertain about when they will be vaccinated. With alarming case counts across the country and new variants of the coronavirus emerging, unions are fighting efforts to return their members to crowded hallways.
The Chicago Teachers Union told members to defy orders to return to the classroom on Monday and to begin working remotely. The teachers say the district has not done enough to keep students and teachers safe during the pandemic. Students are supposed to come back to classrooms on Feb. 1.
Given the seemingly intractable health and labor challenges, some district officials have begun to say out loud what was previously unthinkable: that schools may not be operating normally for the 2021-22 school year. And some labor leaders are seeking to tamp down the expectations Mr. Biden’s words have raised.
“We don’t know whether a vaccine stops transmissibility,” said Randi Weingarten, president of the American Federation of Teachers, the nation’s second-largest teachers union.
Some virus experts, however, have said there is reason to be optimistic on this question.
Ms. Weingarten said a key to returning teachers to classrooms in the coming months would be promises to allow those with health conditions, or whose family members have compromised immune systems, to continue to work remotely; the collection of centralized data on the number of coronavirus cases in specific schools; and assurances from districts that they would shut down schools when cases occur.
Fights over those very demands have slowed and complicated reopenings across the country.
Mr. Biden’s executive order directs federal agencies to create national school reopening guidelines, to support virus contact tracing in schools and to collect data measuring the impact of the pandemic on students. The White House is also pushing a stimulus package that would provide $130 billion to schools for costs such as virus testing, upgrading ventilation systems and hiring staff members.
Research has pointed to the potential to operate schools safely before teachers and students are vaccinated, as long as practices like mask wearing are adhered to, and especially when community transmission and hospitalization rates are controlled.
An 8-year-old girl in Missouri is getting an earful from frustrated Arizonans who are trying to get inoculated against Covid-19 and mistakenly calling her instead.
Sophia Garcia of Sullivan, Mo., who used to live in Arizona, has been receiving dozens of calls from people in the state on her hand-me-down phone, whose Phoenix number is just one digit different from the Arizona health department’s vaccine help line.
“Every five minutes my phone keeps ringing,” she told Phoenix’s CBS affiliate, KPHO/KTVK. Callers have been complaining about scheduling difficulties and asking how to book an appointment, her family said. In response, Sophia has recorded a voice mail message directing callers to the appropriate number.
Her story offers a glimpse of the struggles and at times desperation of people seeking vaccination in Arizona and elsewhere. People across the United States have complained of their second dose appointments being canceled after vaccination sites ran out of supplies. And there are concerns that President Biden’s goal of 100 million shots in 100 days may not be ambitious enough.
Arizona, which has the worst infection rate in the country, is speeding up vaccinations after a slow start, with the Department of Health Services announcing on Sunday that more than 400,000 doses had been administered. Over 61,000 people have received both doses, the health department said. A New York Times tracker monitoring the vaccine rollout in each state places Arizona in the top 20 for doses administered.
After earlier glitches and staff shortages, the state attributes the turnaround partly to round-the-clock use of the State Farm Stadium in Glendale, a suburb of Phoenix, as a site for inoculations in the past few weeks. “The success of our State Farm Stadium vaccination site has made it clear that Arizona can efficiently and effectively administer vaccine to large numbers,” Dr. Cara Christ, director of the Arizona Department of Health Services, said in a statement.
Another vaccination site at the Phoenix Municipal Stadium is set to open next week.
State officials said the federal government had denied a request for an additional 300,000 doses each week. “Now the federal government has to step up its game and provide additional vaccine to support Arizona’s proven momentum,” Dr. Christ said.
In the meantime, Arizonans who inadvertently call Sophia in Missouri will get this firm but encouraging message: “Hopefully, if you try carefully, you could get the right number.”
Carolyn Zain had heard horror stories about the nation’s coronavirus vaccine rollout: long waits, clunky websites, people being turned away. So when her health department announced it was expanding appointments, she armed herself with two phones and held her breath.
Within 20 minutes, she secured a slot for the next day. She arrived for her 2 p.m. appointment and was resting in a chair, a fresh shot in her arm, by 2:21 p.m.
“It went wonderfully,” said Ms. Zain, 79, who, after a year spent mostly home alone, wore a sequined face mask that shimmered like confetti for her appointment at a Charleston clinic last week.
Since the United States began distributing vaccines more than a month ago, it has moved far more slowly than officials had hoped. But West Virginia has stood out for its success in getting people vaccinated. About 9 percent of all West Virginians have received a first dose of the coronavirus vaccine, a larger segment than in every state but Alaska and double the rate of some.
No state has given a larger share of its residents second doses, a crucial step to securing the best chance at immunity.
While many states are struggling to hand out the shots that the federal government has provided to them, West Virginia has given out 83 percent of its doses, by far among the highest. Many states so far have struggled to give even half of their allotted vaccines.
“West Virginia is about at the top of the charts,” said Dr. Mark McClellan, a former commissioner of the U.S. Food and Drug Administration. “We need to get more states to the point that they have the vaccination capacity of West Virginia.”
The state also provides a glimpse at a fundamental problem that looms for the country: Even the most efficient state vaccine operations do not have enough shots for all who want them.
Dr. Clay Marsh, the state coronavirus czar, estimated that West Virginia had the capacity to handle 125,000 doses a week, but was getting just 23,600.
Early on, the state got a significant head start because it initially opted out of a federal program to vaccinate people in nursing homes and other long-term care facilities.
The federal plan teamed up with Walgreens and CVS to inoculate people in nursing homes around the country, but many communities in West Virginia are far from the nearest big box store, and about half of pharmacies are independently owned.
West Virginia created a network of pharmacies in the state, pairing them with about 200 long-term care facilities. As a result, West Virginia finished its first round of vaccinations at nursing homes last month, while many states were just getting started.
Central to the state’s strategy, too, is putting the National Guard at the helm of vaccine operations.
Officials say they have also learned what not to do, including not promising shots they do not yet have. In Charleston, appointments are not made until county officials have that week’s allotment of vaccines on hand, sitting in their own freezer.
Global Roundup
An official in the northeastern Chinese city of Tonghua, where residents are barred from leaving their homes amid a strict lockdown, apologized to residents who said they had not been receiving enough food.
Tonghua, an industrial city of about two million people in Jilin Province, went into lockdown on Jan. 20 after the number of recent cases grew to nearly 100. Since then the local outbreak has been largely brought under control, with just two new symptomatic cases reported on Saturday.
As China observes the first anniversary of the lockdown in Wuhan, the central city where the virus was first discovered, other parts of the country are confronting smaller outbreaks. The government has responded with mass testing and citywide lockdowns that at one point affected more than 28 million people, almost three times the size of the population that was initially locked down in Wuhan.
On Monday, China reported 124 new cases in the previous 24 hours, including 117 local cases and seven among travelers in quarantine after returning from overseas. That is an increase from 80 cases reported a day earlier, though still vastly lower than other large countries. Mainland China, which has a population of 1.4 billion people, has recorded a total of about 100,000 coronavirus cases and 4,635 deaths, according to a New York Times database.
In Tonghua, the tough restrictions on movement have led to widespread complaints, with residents taking to social media to vent and seek help. Jiang Haiyan, a deputy mayor, acknowledged the problems on Sunday, saying that a lack of personnel had hindered the distribution of supplies.
“At present, there are problems of untimely and inadequate distribution of household materials for citizens, which has caused great inconvenience to everyone’s lives,” Ms. Jiang said.
The city’s Communist Party committee and local government “express their sincere apologies to everyone,” she added.
The city had since recruited a large number of community workers and volunteers to ensure adequate supply distribution, Ms. Jiang said.
But on the social media accounts for The People’s Daily, the Communist Party’s main newspaper, some people continued to express dissatisfaction with the situation.
“Before the residents weren’t treated humanely, they didn’t tell us anything and in one night went from house to house sealing everything up,” read one popular reply. “Now grass-roots officials and volunteers are treated inhumanely, and in one night all the food must be distributed door to door.”
Livia Albeck-Ripka, Christopher F. Schuetze, and Lin Qiqing contributed reporting.
In other developments around the world:
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Officials in New Zealand confirmed on Monday a case of the South African variant of the coronavirus in a returned traveler a week after she left hotel quarantine. Officials have said the 56-year-old, who had tested negative twice before being allowed to return home, was probably infected by a fellow returned traveler while in quarantine. People who were at the same hotel have been urged to self-isolate immediately. It is the first case New Zealand has recorded outside quarantine since November. The government in Australia responded on Monday by suspending its travel bubble with New Zealand for at least 72 hours, saying all travelers from the country must quarantine on arrival.
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A Berlin hospital was forced to lock down and put its entire staff in quarantine, after 20 cases of the new British variant of the coronavirus were found among patients and hospital workers. The hospital, Vivantes Humboldt-Klinikum, in the northwestern neighborhood of Reinickendorf, stopped taking new patients on Friday night and has put its entire staff — as many as 1,700 nurses, doctors, caregivers, support staff and administrators — under quarantine. Those required to come to work who do not have private means of transportation are using specially organized ride-hailing services to avoid coming into contact with the population at large.
With the snap of the snare drums, New Orleanians take joyous turns high-stepping and chicken strutting, dressed in the finery of their social clubs and krewes. The celebration, shown on a 30-second public service announcement, is one of numerous efforts around the country to persuade people to get inoculated against the coronavirus. But its homegrown approach, using neighborhood personas and invoking local Carnival culture, may make it particularly effective, say experts in vaccine hesitance and behavioral change.
“I’m getting the vaccine so we can have Mardi Gras, y’all!” shouts Jeremy Stevenson, a Monogram Hunter Mardi Gras Indian, also known as Second Chief Lil Pie, as he sways in a 12-foot tower of turquoise feathers and beading.
Other locals prance forth to offer their own reasons, concluding: “Sleeves Up, NOLA!”
“I teared up several times and also just laughed out loud with delight. The sense of community is contagious,” said Alison M. Buttenheim, the scientific director of the Center for Health Incentives and Behavioral Economics at the University of Pennsylvania. “Vaccination is framed as a collective action that everyone can contribute to in order to bring back things the community values and cherishes.”
Although national vaccine hesitation rates are falling, surveys show that antipathy to the new shots is still widespread among some demographic groups. But there has been little consensus around ways to build confidence in the shot.
In November, New Orleans put together a coalition of public health doctors, clergy, leaders from Black, Latino and Vietnamese communities, and heads of the city’s large social clubs. The group identified cultural icons that would appeal widely to residents.
Rather than focusing messaging on the miseries wrought by the pandemic, it decided to emphasize an aspirational and inviting tone, a core insight derived from behavioral change research.
“I’m getting my shot so I can visit my 92-year-old mom and we can eat in our favorite restaurants,” says Julie Nalibov of the Krewe of Red Beans.
The spot will be shown on local TV stations and saturate social media. Photographs will adorn citywide billboards.
“I hope state and local health departments around the country can get resources to develop more hyperlocal campaigns,” Dr. Buttenheim said. “Imagine similar spots from Philly, or Boise, or Hawaii, or the Cherokee Nation.”
Prime Minister Mark Rutte of the Netherlands said on Monday that anyone involved in riots over the weekend protesting the country’s coronavirus measures had engaged in “criminal violence” and warned that perpetrators would be treated accordingly.
Hundreds of people were detained during unrest in Amsterdam, Eindhoven and at least eight other cities after the start of a 9 p.m. curfew on Saturday, the police said. Officers used tear gas, attack dogs and water cannons to disperse crowds in the southern city of Eindhoven, where shops were looted and cars set on fire. In Urk, a staunchly protestant fishing village young people burned down a Covid test facility.
“This has nothing to do with protest or fighting for freedom,” Mr. Rutte, told reporters on Monday. “This is criminal violence, and we will treat it as such.”
His caretaker government implemented harsh new lockdown measures last week, vetted by Parliament, to curb the spread of the coronavirus. Flights to Britain, South Africa and most of South America were halted on Saturday. It also implemented a nationwide curfew, the first since World War II.
The mayor of Eindhoven, John Jorritsma, was visibly upset when he spoke to reporters about the violence in the city. He called the rioters “scum of the earth” and said he feared the Netherlands, normally one of the quietest countries in the European Union, was “on a path of civil war.”
A spokesman for the Dutch police union said the group feared that the illegal protests and riots were just the start of the curfew-related unrest. “I hope it was a one-off, but I’m afraid it was a harbinger for the coming days and weeks,” the spokesman, Koen Simmers, said, according to the public broadcaster NOS. “We haven’t seen so much violence in 40 years,” he added.
The protesters also gathered last week in Amsterdam after calls on social media to “resist” the lockdown rules and the government’s policies overall. Mr. Rutte is one of the longest-serving European leaders. Elections in the Netherlands are scheduled for March.
Protests also erupted over the weekend in Denmark. Five people were arrested on Saturday during an anti-lockdown demonstration in Copenhagen, local news outlets reported. Around 1,000 protesters gathered to demonstrate against what they said were limitations of their freedoms, after a call for protest by a Facebook group. Protesters tied an effigy of Prime Minister Mette Frederiksen to a pole and burned it, Danish channel TV2 reported. A sign was hung around the effigy’s neck saying, “She must and should be killed.”
Ukraine reopened schools, restaurants and movie theaters on Monday after testing showed the coronavirus was spreading less rapidly after just one week of a strict lockdown.
The health minister, Maksym Stepanov, pointed to the improving statistics as a clear indication that a strict lockdown, even if brief, can tamp down numbers. The rate of new infections declined about a third after the first seven days of closures, he said.
The cumulative number of infections nationwide last week was just over 30,000, nearly 14,000 less than the week before, Mr. Stepanov said. “The statistics are relatively optimistic and point to an improvement in the situation,” he said, local media reported.
Mr. Stepanov also pointed to a decline in hospitalizations, which typically trail infections by several weeks, suggesting that the downward trend had begun before the lockdowns and that New Year celebrations had not shifted the dynamic.
President Volodymyr Zelensky quickly imposed lockdowns last spring before easing them over the summer. The country retained a system that can close businesses in cities or regions with flare-ups.
Though the government lifted some restrictions on Monday, not all businesses can open. Nightclubs and sports stadiums remain closed. Schools are not allowed convene large gatherings of students, such as for performances or schoolwide meetings.
Ukraine, which aspires to join the European Union but is not in the bloc, has struggled to find vaccines and may not be able to inoculate its population until well into the year, forcing it to rely on quarantines, lockdowns and other restrictions until then.
Mayor Bill de Blasio of New York City announced on Monday that the openings of planned mass coronavirus vaccination sites at Yankee Stadium and Citi Field would be postponed because of the low supply of doses available.
“We want to get those to be full blown, 24-hour operations,” Mr. de Blasio said at a news conference, “but we don’t have the vaccine.”
The site at Citi Field had been set to launch this week, while plans for the one in the Bronx were still being developed. Another site at the Empire Outlets on Staten Island was initially scheduled to open last week, but would also be postponed, the mayor said.
The city had a total of 19,032 first doses in inventory on Monday morning, Mr. de Blasio said, and expects to receive just under 108,000 doses this week. But he continued to warn that figure was not nearly enough to keep up with the pace at which New Yorkers are being inoculated: If the supply was greater, the mayor said New York City would be on pace to administer roughly 500,000 doses per week.
Instead, he said many inoculation appointments will continue to be canceled or rescheduled as they were last week.
Some public health experts have worried that the limited supply could undermine goals of state and city officials to prioritize communities hard hit by the virus — Black and Latino people and low-income New Yorkers — in the vaccine rollout.
The state has not released demographic information on the distribution, but Mr. de Blasio said on Monday that data would come “this week,” adding that “it’s part of making sure that we act to address the disparities that have pervaded the Covid experience.”
The mayor last week also sent a letter to President Biden requesting more doses, along with the “flexibility” to use second doses to increase the pace of vaccinations. He did not discuss any specific progress made on Monday, but appeared hopeful that an update could come soon.
“What is so clear now is the commitment of the Biden administration,” Mr. de Blasio said, “to finding every conceivable way to get us more vaccine quickly. We are waiting in the course of this week for more detailed information.”
But federal health officials and corporate executives agree that the immediate supply is unlikely to increase before April because of manufacturing constraints. Public health officials are also awaiting clinical trial results for the vaccine under development by Johnson & Johnson, which city officials said on Monday they hoped would also raise supply levels.
Still, the current vaccination effort has so far sown confusion and frustration across the country as other states similarly struggle with shortages.
And as small businesses across New York City continue to collapse during the pandemic, Mr. de Blasio said the city’s annual restaurant week started on Monday with a focus on takeout and delivery options.
“There’s a lot of things we need to keep doing to help our business in the meantime,” he said, “as they work to survive.”
Google said it will make company buildings, parking lots and open spaces available to serve as temporary vaccination clinics in partnership with health care providers and public health officials.
In a blog post on Monday, Sundar Pichai, the chief executive of Google’s parent company, Alphabet, said the company will start by opening sites in Los Angeles, the San Francisco Bay Area and New York City, with plans to expand to other sites nationwide.
The move is part of a series of measures to help accelerate vaccination efforts. Google also said it plans to contribute $100 million in ad credits to health organizations to educate people about the vaccine and $50 million for groups working on fair access to the vaccine.
It will also include more information in search results and maps to help people find vaccination locations with details about who is eligible and whether appointments are necessary. Google said it will provide local distribution information in search results in the coming week so people can determine whether they are eligible to receive a vaccine.
